Steroid osteoporosis.
نویسندگان
چکیده
منابع مشابه
Steroid-induced osteoporosis.
INTRODUCTION Corticosteroids have major effects on calcium metabolism, leading to accelerated osteoporosis and fracture. METHODS This review will attempt to summarise current knowledge about their effects in light of new information and important remaining questions, especially with respect to management of this common condition. RESULTS Corticosteroids affect bone through multiple pathways...
متن کاملManagement of Steroid-Induced Osteoporosis
Chronic use of corticosteroid is the most common secondary cause of osteoporosis. Contrary to previous belief apart from the primary or the idiopathic type, it occurs in all racial groups, both genders, and at any age. In a large cross sectional study in which 229 corticosteroid users (mean age 61 years, ≥6 months of prednisone, ≥5 mg/day) were compared with 286 controls not taking corticostero...
متن کاملHow to prevent steroid induced osteoporosis.
The first choice for prevention of corticosteroid osteoporosis is a potent oral bisphosphonate-for example, alendronate or risedronate. Intravenous bisphosphonates should be considered for patients intolerant of the oral route. For patients receiving chronic low dose corticosteroids treatment with calcium and vitamin D may prevent further bone loss. Use of parathyroid hormone is promising.
متن کاملRecent Advances in the Management of Steroid Induced Osteoporosis
Correspondence to: Lai-Wa Kwok Abstract: Glucocorticoid-induced osteoporosis is the most common cause of drug-induced osteoporosis, leading to fragility fractures, decrease in mobility and quality of life. Patients who receive equivalent dose of prednisolone 5 mg for more than six months are at risk of glucocorticoid-induced osteoporosis, but there is no conclusive evidence for a safe cutoff fo...
متن کاملDefective fracture healing in OVX and steroid- induced osteoporosis
The physiological mechanisms of fracture healing have been the topic of active investigation for many years. At the present time ample data exist on the histological, mechanical and biochemical aspects of this process. Most investigators now believe that many of the steps in fracture healing are a recapitulation of what happens in endochondral bone formation. What lies ahead for a better unders...
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ژورنال
عنوان ژورنال: BMJ
سال: 1993
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.307.6903.519